At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs, but few options.

Neurocrine Biosciences is a neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, endocrine and psychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, Parkinson's disease, endometriosis* and uterine fibroids*, as well as clinical programs in multiple therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. *in collaboration with AbbVie

About the Role:

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• Performs assigned experiments that support scientific activities and project goals, may design less complex experiments

• Follows appropriate methods and techniques in performing experiments and prepares related reports

• Collaborates with supervisory personnel to develop routine methods

• Recommends alternatives, researches new methods and techniques and may proactively seek out senior personnel to discuss potential solutions

• Responsible for cell-based or biochemical assay development, including primary cells and tissues, with some supervision

• Maintains SOP's and writes data summaries for experiments conducted

• Reviews, comprehends and complies with all SOP's, and safety and quality assurance standards at all times

• Provides training and/or supervision to junior staff, as needed

• Gene Therapy specific work will include support of Gene Therapy projects from inception to IND-enabling studies. Work with the R&D team to design and implement in vitro and in vivo strategies for development of Gene Therapies and to measure potency and efficacy. Remain current with the latest developments in Gene Therapy technologies, and support their implementation. Prepares detailed data reports and present results to peers, colleagues, and collaborators

• Other duties as assigned

• BS/BA degree in biology and 2+ years of relevant experience OR

• MS/MA degree in biology and some relevant industry experience preferred OR

• PhD or equivalent and some relevant experience preferred

• Gene Therapy position will require a minimum of 2 years of postdoctoral experience in gene therapy

• Knowledge of the principles of biology and chemistry, including pharmacology & cell biology

• Experience with tissue culture techniques, including aseptic technique, primary and immortalized cell line development & management

• Basic knowledge of NGS technologies, their implementation, and data analysis & relevant statistical tests

• Gene manipulation techniques, including cloning, sequencing, use of gene expression manipulation technologies (may include experience with ASO, siRNA, miRNA, AAV transduction)

• Knowledge of tissue processing techniques for detection of gene and protein expression, including fixation, sectioning, IHC, histological staining, ISH

• Recognizes fundamental anomalies in data points and identifies issues in experiments / processes

• Begins to understand how to think outside of the technical process and consider the impact decisions will have on the broader scientific goals

• Strong knowledge of one scientific discipline

• Good knowledge of scientific principles, methods and techniques

• Good knowledge and demonstrated ability working with a variety of laboratory equipment/tools

• Ability to work as part of a team.

• Strong computer skills

• Good communications, problem-solving, analytical thinking skills

• Detail oriented

• Ability to meet deadlines

• Good project management skills

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Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.

We are committed to building a diverse, equitable, and inclusive workplace, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description.

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